Welcome to Korbax Pharmasules — We at Korbax Pharmasules has all the department like – Quality assurance, Quality control, Regulatory, Formulation development and production. Which assures the quality of the products we manufacture.
Welcome to Korbax Pharmasules — We at Korbax Pharmasules has all the department like – Quality assurance, Quality control, Regulatory, Formulation development and production. Which assures the quality of the products we manufacture.
Lansoprazole is used to reduce gastric acid secretion and is approved for short term treatment of active gastric ulcers, active duodenal ulcers, erosive reflux oesophagitis, symptomatic gastroesophageal reflux disease, and non-steroidal anti-inflammatory drug (NSAID) induced gastric and duodenal ulcers. 14Label It may be used in the maintenance and healing of several gastric conditions including duodenal ulcers, NSAID related gastric ulcers, and erosive esophagitis.Label Lansoprazole prevents recurrence of gastric ulcers in patients who have a documented history of gastric ulcers who also use NSAIDs chronically. Label Predictably, it is also useful in the management of hypersecretory conditions including Zollinger-Ellison syndrome. Label Lansoprazole is effective at eradicating H. pylori when used in conjunction with amoxicillin and clarithromycin (triple therapy) or with amoxicillin alone (dual therapy) Pharmacodynamics
Lansoprazole decreases gastric acid secretion by targeting H+,K+-ATPase, which is the enzyme that catalyzes the final step in the acid secretion pathway in parietal cells. 6 Conveniently, lansoprazole administered any time of day is able to inhibit both daytime and nocturnal acid secretion.6 The result is that lansoprazole is effective at healing duodenal ulcers, reduces ulcer-related pain, and offers relief from symptoms of heartburn 6 Lansoprazole also reduces pepsin secretion, making it a useful treatment option for hypersecretory conditions such as Zollinger-Ellison syndrome.
The oral bioavailability of lansoprazole is reported to be 80-90%2 and the peak plasma concentration (Cmax) is achieved about 1.7 hours after oral dosing. Label Food reduces the absorption of lansoprazole (both Cmax and AUC are reduced by 50-70%); therefore, patients should be instructed to take lansoprazole before meals.
Korbax Pharmasules has established a plant for manufacturing of different type of pellets, Capsules and other dosages forms related to pharmaceuticals to serve the human being.
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